ZRSR2P1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZRSR2P1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZRSR2P1-associated genes across cancer lineages are p62 Lck ligand, EGFR_pY1068, and eIF4E. Each is linked with ZRSR2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZRSR2P1-to-partner and partner-to-ZRSR2P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRSR2P1→partner) and Y-score (partner→ZRSR2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp62 Lck ligand →+0.536+3.321<.001<.00132
UCECEGFR_pY1068 →-0.189-1.765.044.01431
UCECeIF4E →+0.252+2.662.001<.00131
UCECeIF4G →+0.304+2.222.008.01031
UCECERK2 →+0.205+2.459.004.01831
UCECFoxM1 →+0.255+1.765.008.01431
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration