Across TCGA pan-cancer cohorts, ZRSR2P1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ZRSR2P1’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ZRSR2P1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZRSR2P1 is over-expressed in tumor, although a few such as BLCA and LUSC show the opposite, repressed pattern.
BLCA, LUSC, and CHOL are the cancer types where ZRSR2P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZRSR2P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.