ZRANB2

Across TCGA patient cohorts, ZRANB2 mutation is significantly associated with the RNA expression of many other genes, with 1,093 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZRANB2-associated genes across cancer lineages are SPCS2P2, OR5F1, and OR2V1. Each is linked with ZRANB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZRANB2-to-partner and partner-to-ZRANB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPCS2P2 grouped by ZRANB2-low versus ZRANB2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRANB2→partner) and Y-score (partner→ZRANB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SPCS2P2 →	+0.139	+5.594	<.001	.004	3	2
HNSC	OR5F1 →	+0.027	+4.754	.001	.005	3	2
HNSC	OR2V1 →	+0.066	+3.716	<.001	.008	3	2
LUAD	OR8B9P →	+0.044	+4.376	.002	.002	3	2
CESC	FOXL3 →	+0.218	+3.411	<.001	.009	3	2
LUSC	RNU6-622P →	+0.350	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,093 associations by consensus.

SPCS2P2 by ZRANB2 expression — SKCM

Explore this box plot interactively →