ZRANB1

Across TCGA cell cohorts, ZRANB1 mutation is significantly associated with the RNA expression of many other genes, with 312 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZRANB1-associated genes across cancer lineages are ANKRD54, DEPDC5, and CBY1. Each is linked with ZRANB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZRANB1-to-partner and partner-to-ZRANB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD54 grouped by ZRANB1-low versus ZRANB1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZRANB1→partner) and Y-score (partner→ZRANB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD54 →	+0.531	+3.451	.001	.002	3	1
LARGE_INTESTINE	DEPDC5 →	+0.522	+3.364	.009	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.543	+3.137	.005	.007	3	1
LARGE_INTESTINE	TRMU →	+0.570	+3.364	.004	.002	3	1
LARGE_INTESTINE	DESI1 →	+0.516	+3.451	.002	.002	3	1
LARGE_INTESTINE	DDHD1 →	+0.675	+3.364	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 312 associations by consensus.

ANKRD54 by ZRANB1 expression — LARGE_INTESTINE

Explore this box plot interactively →