Across TCGA cell cohorts, ZPBP2 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZPBP2-associated genes across cancer lineages are IFNG, HRG, and SV2C. Each is linked with ZPBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZPBP2-to-partner and partner-to-ZPBP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZPBP2→partner) and Y-score (partner→ZPBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNG →	+0.156	+3.567	<.001	.003	3	1
BLOOD_Leukemia	HRG →	+0.321	+4.177	<.001	.001	3	1
BLOOD_Leukemia	SV2C →	+0.419	+3.504	<.001	.009	3	1
BLOOD_Leukemia	SPATA19 →	+0.015	+4.569	<.001	.003	3	1
BLOOD_Leukemia	MS4A15 →	+0.100	+3.857	.008	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.171	+4.289	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZPBP2 survival (RNA) · tumor vs normal (RNA) · all ZPBP2 data types