ZPBP

Across TCGA cell cohorts, ZPBP RNA expression is significantly associated with the go_rna of many other GO terms, with 295 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ZPBP-associated GO terms across cancer lineages are Determination of left/right symmetry, Electron transport chain, and Proton motive force-driven mitochondrial ATP synthesis. Each is linked with ZPBP in more than 2 cancer types. Because this analysis shows association rather than direction, both ZPBP-to-partner and partner-to-ZPBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Determination of left/right symmetry grouped by ZPBP-low versus ZPBP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZPBP→partner) and Y-score (partner→ZPBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Determination of left/right symmetry →	-0.047	-0.063	<.001	.009	3	3
OVARY	Electron transport chain →	+0.121	+0.044	<.001	.003	3	3
OVARY	Proton motive force-driven mitochondrial ATP synthesis →	+0.105	+0.029	<.001	.005	3	3
BLOOD_Myeloma	Pyrimidine-containing compound salvage →	-0.136	-0.099	.002	.006	3	3
LUNG_NSCLC_LUAD	Response to stilbenoid →	+0.161	+0.025	<.001	.009	3	2
LUNG_NSCLC_LUAD	Embryonic digit morphogenesis →	-0.074	-0.025	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 295 associations by consensus.

Determination of left/right symmetry by ZPBP expression — LUNG_SCLC

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