ZP4

Across TCGA patient cohorts, ZP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,584 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZP4-associated GO terms across cancer lineages are Negative regulation of response to wounding, Response to interleukin-1, and Response to mechanical stimulus. Each is linked with ZP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZP4-to-partner and partner-to-ZP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of response to wounding grouped by ZP4-low versus ZP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP4→partner) and Y-score (partner→ZP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of response to wounding →	+0.037	+0.056	<.001	<.001	3	8
STAD	Response to interleukin-1 →	+0.046	+0.077	<.001	<.001	3	8
STAD	Response to mechanical stimulus →	+0.042	+0.063	<.001	<.001	3	8
STAD	Fibroblast proliferation →	+0.061	+0.063	<.001	<.001	3	8
STAD	Regeneration →	+0.045	+0.055	<.001	<.001	3	8
STAD	Cellular response to radiation →	+0.061	+0.045	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,584 associations by consensus.

Negative regulation of response to wounding by ZP4 expression — STAD

Explore this box plot interactively →