ZP4

Across TCGA cell cohorts, ZP4 RNA expression is significantly associated with the drug of many other genes, with 76 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZP4-associated genes across cancer lineages are 5-Fluorouracil, CCT245467, and Savolitinib. Each is linked with ZP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZP4-to-partner and partner-to-ZP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 5-Fluorouracil grouped by ZP4-low versus ZP4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP4→partner) and Y-score (partner→ZP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	5-Fluorouracil →	-0.585	-0.372	.008	.049	3	3
UPPER_AERODIGESTIVE_TRACT	CCT245467 →	-0.705	-0.545	.002	.020	3	3
OESOPHAGUS	Savolitinib →	+0.678	+0.010	.025	.046	3	3
BLOOD_Myeloma	AZD1332 →	+0.950	+0.021	.002	.027	3	3
BLOOD_Myeloma	GSK1070916 →	+1.075	+0.023	.002	.026	3	3
BLOOD_Myeloma	C-75 →	+0.558	+0.026	.022	.015	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

5-Fluorouracil by ZP4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →