ZP4

Across TCGA cell cohorts, ZP4 mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZP4-associated genes across cancer lineages are OR10V1, SGTA, and CNTNAP1. Each is linked with ZP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZP4-to-partner and partner-to-ZP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by ZP4-low versus ZP4-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP4→partner) and Y-score (partner→ZP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR10V1 →	+0.027	+4.285	<.001	.007	3	1
LUNG_NSCLC_LUAD	SGTA →	-0.405	-3.321	.001	.004	3	1
LUNG_NSCLC_LUAD	CNTNAP1 →	-1.068	-3.459	.005	.002	3	1
LUNG_NSCLC_LUAD	LRRC59 →	-0.530	-2.528	<.001	.003	3	1
LUNG_NSCLC_LUAD	STAM2 →	-0.467	-3.032	.002	.009	3	1
LUNG_NSCLC_LUAD	P3H1 →	-0.783	-3.169	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

OR10V1 by ZP4 expression — STOMACH

Explore this box plot interactively →