ZNRF2

Across TCGA patient cohorts, ZNRF2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,183 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNRF2-associated genes across cancer lineages are CFAP91, GK, and C12orf73. Each is linked with ZNRF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNRF2-to-partner and partner-to-ZNRF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNRF2 versus CFAP91 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRF2→partner) and Y-score (partner→ZNRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CFAP91 →	-0.942	-0.375	<.001	.001	3	3
OV	GK →	+0.778	+0.376	.002	.006	3	3
UCEC	C12orf73 →	-0.366	-0.298	.001	.002	3	3
OV	SKAP2 →	+0.706	+0.281	.007	.008	2	4
UCEC	PRELID3A →	-0.664	-0.299	<.001	<.001	3	3
BRCA	JAGN1 →	-0.404	-0.329	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,183 associations by consensus.

ZNRF2 vs CFAP91 — UCEC

Explore this scatter interactively →