ZNF879

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF879 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF879 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZNF879 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF879 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and KICH are the cancer types where ZNF879 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianII,III,IV1.0000.471.00434view →
KICHDFSMedianAll0.1020.848.00413view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZNF879–UCEC (DFS)

Kaplan–Meier survival curve for ZNF879 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration