ZNF878

Across TCGA patient cohorts, ZNF878 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,823 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF878-associated proteins across cancer lineages are RFC2, XAB2, and RFC1. Each is linked with ZNF878 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF878-to-partner and partner-to-ZNF878 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF878 versus RFC2 in LSCC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF878→partner) and Y-score (partner→ZNF878) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.407	+0.585	<.001	<.001	3	5
LSCC	XAB2 →	+0.269	+0.538	<.001	<.001	3	5
GBM	RFC1 →	+0.359	+0.563	<.001	<.001	3	4
LSCC	RFC1_S368 →	+0.925	+0.667	<.001	<.001	3	4
GBM	RFC3 →	+0.413	+0.527	<.001	<.001	3	4
LSCC	RFC4 →	+0.485	+0.520	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,823 associations by consensus.

ZNF878 vs RFC2 — LSCC

Explore this scatter interactively →