ZNF878

Across TCGA patient cohorts, ZNF878 mutation is significantly associated with the RNA expression of many other genes, with 4,845 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF878-associated genes across cancer lineages are MIR6793, BNIP3P6, and MIR3173. Each is linked with ZNF878 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF878-to-partner and partner-to-ZNF878 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6793 grouped by ZNF878-low versus ZNF878-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF878→partner) and Y-score (partner→ZNF878) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6793 →	+0.707	+3.747	.005	.006	3	3
READ	BNIP3P6 →	+0.352	+4.925	<.001	.004	3	2
READ	MIR3173 →	+0.602	+4.533	.003	.004	3	2
UCEC	KRT17P1 →	+0.070	+1.606	.001	.001	3	2
BLCA	SNRPGP17 →	+0.342	+3.934	<.001	.002	3	2
BLCA	CTAGE6 →	+0.126	+3.584	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,845 associations by consensus.

MIR6793 by ZNF878 expression — BRCA

Explore this box plot interactively →