Across TCGA pan-cancer cohorts, ZNF877P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ZNF877P’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where ZNF877P RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF877P is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
COAD are the cancer types where ZNF877P tumor–normal differential expression is most reproducible.