ZNF865

Across TCGA cell cohorts, ZNF865 mutation is significantly associated with the RNA expression of many other genes, with 1,378 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF865-associated genes across cancer lineages are PBK, ZFP2, and VWA5B1. Each is linked with ZNF865 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF865-to-partner and partner-to-ZNF865 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PBK grouped by ZNF865-low versus ZNF865-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF865→partner) and Y-score (partner→ZNF865) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PBK →	+0.848	+3.321	<.001	.002	3	3
LARGE_INTESTINE	ZFP2 →	+0.445	+3.129	<.001	<.001	3	3
OVARY	VWA5B1 →	+0.021	+3.263	.009	.006	3	2
LARGE_INTESTINE	FAM149A →	+1.170	+2.364	<.001	<.001	3	2
BLOOD_Leukemia	C12orf57 →	+0.980	+2.630	<.001	.002	3	2
BLOOD_Leukemia	ARL6 →	+0.606	+2.252	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,378 associations by consensus.

PBK by ZNF865 expression — LARGE_INTESTINE

Explore this box plot interactively →