ZNF862

Across TCGA cell cohorts, ZNF862 mutation is significantly associated with the RNA expression of many other genes, with 760 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF862-associated genes across cancer lineages are DNAAF6, TBC1D32, and TMEM272. Each is linked with ZNF862 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF862-to-partner and partner-to-ZNF862 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAAF6 grouped by ZNF862-low versus ZNF862-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF862→partner) and Y-score (partner→ZNF862) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DNAAF6 →	+0.030	+3.015	.001	.006	3	3
LARGE_INTESTINE	TBC1D32 →	+0.766	+2.523	.001	.003	3	3
LARGE_INTESTINE	TMEM272 →	+0.074	+2.606	.001	.003	3	2
SKIN	KHDC3L →	+0.013	+3.310	<.001	<.001	3	2
BLOOD_Lymphoma	ADRA1A →	+0.170	+4.459	<.001	.001	3	2
BLOOD_Lymphoma	SLC25A31 →	+0.038	+3.523	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 760 associations by consensus.

DNAAF6 by ZNF862 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →