ZNF852

Across TCGA patient cohorts, ZNF852 protein abundance is significantly associated with the RNA expression of many other genes, with 717 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF852-associated genes across cancer lineages are ARHGAP5, PARP4, and LY6K. Each is linked with ZNF852 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF852-to-partner and partner-to-ZNF852 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF852 versus ARHGAP5 in UCEC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF852→partner) and Y-score (partner→ZNF852) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARHGAP5 →	+0.710	+0.943	.007	<.001	3	1
UCEC	PARP4 →	-0.980	-1.096	.002	.001	3	1
LSCC	LY6K →	-1.322	-0.522	<.001	.003	2	2
UCEC	P2RY6 →	-1.129	-0.659	.006	.007	3	1
UCEC	PTPRM →	-2.015	-0.729	<.001	.004	3	1
UCEC	KLK12 →	+2.720	+0.877	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 717 associations by consensus.

ZNF852 vs ARHGAP5 — UCEC

Explore this scatter interactively →