ZNF852

Across TCGA cell cohorts, ZNF852 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF852-associated genes across cancer lineages are HSCB, MIOX, and CHMP4B. Each is linked with ZNF852 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF852-to-partner and partner-to-ZNF852 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSCB grouped by ZNF852-low versus ZNF852-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF852→partner) and Y-score (partner→ZNF852) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HSCB →	+0.520	+3.169	.008	.009	3	1
LARGE_INTESTINE	MIOX →	+0.287	+3.241	<.001	.007	3	1
LARGE_INTESTINE	CHMP4B →	-0.598	-3.278	.005	.006	3	1
LARGE_INTESTINE	METTL4 →	+0.622	+3.364	.001	.002	3	1
LARGE_INTESTINE	RNF125 →	+1.157	+3.364	<.001	.002	3	1
LARGE_INTESTINE	CA2 →	+1.847	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

HSCB by ZNF852 expression — LARGE_INTESTINE

Explore this box plot interactively →