ZNF85

Across TCGA patient cohorts, ZNF85 protein abundance is significantly associated with the protein abundance of many other proteins, with 324 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF85-associated proteins across cancer lineages are TLE3_T259, UNC119B, and RIC8A_T443. Each is linked with ZNF85 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF85-to-partner and partner-to-ZNF85 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF85 versus TLE3_T259 in GBM, with a Pearson correlation of -0.98.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF85→partner) and Y-score (partner→ZNF85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLE3_T259 →	-0.580	-2.299	.004	<.001	3	1
GBM	UNC119B →	-0.530	-2.450	.002	<.001	3	1
GBM	RIC8A_T443 →	-0.977	-1.926	<.001	<.001	3	1
GBM	RUFY3_T51 →	+0.604	+1.933	.001	<.001	3	1
GBM	CAD →	-0.835	-2.542	.001	<.001	3	1
GBM	CARMIL2_S1268 →	+1.074	+1.849	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 324 associations by consensus.

ZNF85 vs TLE3_T259 — GBM

Explore this scatter interactively →