ZNF85

Across TCGA pan-cancer cohorts, ZNF85 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF85 data layer compared with 2 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ZNF85 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF85 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRC show a favorable association.

OV, KIRC, and UVM are the cancer types where ZNF85 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Quartile	III,IV	0.392	0.275	.003	58	view →
KIRC	DFS	Median	All	0.936	0.788	<.001	54	view →
UVM	DFS	Quartile	III,IV	0.274	0.823	.014	32	view →
MESO	OS	Tertile	All	0.298	0.488	.011	26	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	18	view →
LIHC	DFS	Median	All	0.298	0.536	.001	17	view →
KICH	DFS	Tertile	III,IV	0.301	1.000	.010	16	view →
GBM	DFS	Median	All	0.309	0.209	.008	16	view →
ACC	OS	Tertile	IV	0.871	0.419	.001	15	view →
STAD	DFS	Median	All	0.606	0.825	.003	12	view →
LUSC	DFS	Median	All	0.614	0.703	.020	12	view →
THCA	DFS	Tertile	All	0.955	0.658	.007	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF85–OV (DFS)

Open the OV breakdown →