ZNF85

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF85 mutation is significantly associated with the RNA expression of many other genes, with 3,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF85-associated genes across cancer lineages are RN7SL26P, MIR640, and MIR548H1. Each is linked with ZNF85 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF85-to-partner and partner-to-ZNF85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL26P grouped by ZNF85-low versus ZNF85-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF85→partner) and Y-score (partner→ZNF85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRN7SL26P →+0.327+3.425.004.00933
LIHCMIR640 →+0.295+5.149<.001.00332
LIHCMIR548H1 →+0.561+5.693<.001<.00132
LIHCLINC01072 →+0.129+5.305<.001.00332
BLCASTRADBP1 →+0.037+4.363.008.00732
BLCAHSPE1P1 →+0.562+6.307<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,024 associations by consensus.

RN7SL26P by ZNF85 expression — STAD

Box plot of RN7SL26P in ZNF85-low vs ZNF85-high samples in STAD.

Explore this box plot interactively →

Exploration