ZNF85

Across TCGA cell cohorts, ZNF85 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,971 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF85-associated GO terms across cancer lineages are Regulation of chromosome segregation, Negative regulation of G2/M transition of mitotic cell cycle, and Negative regulation of cell cycle G2/M phase transition. Each is linked with ZNF85 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF85-to-partner and partner-to-ZNF85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome segregation grouped by ZNF85-low versus ZNF85-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF85→partner) and Y-score (partner→ZNF85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of chromosome segregation →	+0.111	+1.732	.004	.007	3	10
URINARY_TRACT	Negative regulation of G2/M transition of mitotic cell cycle →	+0.075	+2.148	.004	.001	3	10
URINARY_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.076	+2.148	.003	.001	3	10
URINARY_TRACT	Mitotic G2/M transition checkpoint →	+0.089	+2.102	.001	.001	3	10
KIDNEY	Cell cycle checkpoint signaling →	+0.053	+1.341	.006	.005	3	10
SOFT_TISSUE	Positive regulation of cell cycle process →	+0.106	+1.171	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,971 associations by consensus.

Regulation of chromosome segregation by ZNF85 expression — URINARY_TRACT

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