ZNF85

Across TCGA cell cohorts, ZNF85 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF85-associated genes across cancer lineages are LRIT2, CTXN3, and RDH8. Each is linked with ZNF85 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF85-to-partner and partner-to-ZNF85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRIT2 grouped by ZNF85-low versus ZNF85-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF85→partner) and Y-score (partner→ZNF85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LRIT2 →	+0.036	+5.087	<.001	.004	3	1
BLOOD_Leukemia	CTXN3 →	+0.012	+5.201	<.001	.006	3	1
BLOOD_Leukemia	RDH8 →	+0.031	+5.201	<.001	.006	3	1
BLOOD_Lymphoma	TEX13B →	+0.043	+4.927	<.001	.001	3	1
BLOOD_Lymphoma	ADIG →	+0.037	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	CCT8L2 →	+0.059	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

LRIT2 by ZNF85 expression — URINARY_TRACT

Explore this box plot interactively →