Across TCGA cell cohorts, ZNF845 mutation is significantly associated with the RNA expression of many other genes, with 272 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF845-associated genes across cancer lineages are MTNR1A, ADAM7, and MCHR2. Each is linked with ZNF845 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF845-to-partner and partner-to-ZNF845 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF845→partner) and Y-score (partner→ZNF845) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MTNR1A →	+0.087	+3.239	<.001	.004	3	2
BLOOD_Leukemia	ADAM7 →	+0.023	+3.507	<.001	.004	3	2
LARGE_INTESTINE	MCHR2 →	+0.013	+2.514	.003	.007	3	2
BLOOD_Myeloma	PF4V1 →	+0.653	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KRTAP8-1 →	+0.099	+4.807	<.001	.006	3	1
BLOOD_Myeloma	TEX28 →	+0.066	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 272 associations by consensus.

Exploration

ZNF845 survival (RNA) · tumor vs normal (RNA) · all ZNF845 data types