zinc finger protein 840, pseudogeneGenealiases: C20orf157 · ZNF840 · dJ981L23.3
Q-omics provides the consensus-scored ZNF840P profile across patient tissues and cancer cell-line models. ZNF840P expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, ZNF840P is differentially expressed in 7, with the highest sampling consensus in UCEC. Additionally, ZNF840P RNA expression shows 15,527 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UVM, UCEC, and THYM as cancer lineages where ZNF840P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF840P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF840P survival associations across molecular data types. ZNF840P RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF840P RNA expression–survival associations across cancer types. High ZNF840P expression shows unfavorable associations in LGG and UCEC, but favorable associations in UVM, KIRP, UCS and BLCA. The UVM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for ZNF840P RNA expression.
This table summarizes ZNF840P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF840P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF840P shows lower tumor expression in UCEC, BRCA, THCA, KIRC, ESCA and KICH. The UCEC box plot shows higher ZNF840P RNA expression in normal versus tumor tissue (log2 FC = −0.463, t-test p < 0.001).
This table shows molecular features associated with ZNF840P in patient tissues and cancer cell lines. In patient samples, ZNF840P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
