ZNF84-DT

Across TCGA patient cohorts, ZNF84-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,063 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZNF84-DT-associated GO terms across cancer lineages are rRNA metabolic process, Regulation of telomere maintenance, and Positive regulation of telomere maintenance. Each is linked with ZNF84-DT in more than 21 cancer types. Because this analysis shows association rather than direction, both ZNF84-DT-to-partner and partner-to-ZNF84-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA metabolic process grouped by ZNF84-DT-low versus ZNF84-DT-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF84-DT→partner) and Y-score (partner→ZNF84-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	rRNA metabolic process →	+0.082	+0.122	<.001	.001	3	22
ESCA	Regulation of telomere maintenance →	+0.071	+0.102	<.001	<.001	3	22
STAD	Positive regulation of telomere maintenance →	+0.071	+0.086	<.001	<.001	3	22
STAD	Macromolecule methylation →	+0.061	+0.082	<.001	<.001	3	22
ESCA	Mitochondrial RNA metabolic process →	+0.063	+0.103	<.001	.001	3	21
ESCA	Transport along microtubule →	+0.060	+0.122	<.001	.002	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,063 associations by consensus.

rRNA metabolic process by ZNF84-DT expression — ESCA

Explore this box plot interactively →