ZNF839

Across TCGA patient cohorts, ZNF839 mutation is significantly associated with the RNA expression of many other genes, with 3,438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF839-associated genes across cancer lineages are HOXC-AS3, MIR646, and IGHD3-16. Each is linked with ZNF839 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF839-to-partner and partner-to-ZNF839 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXC-AS3 grouped by ZNF839-low versus ZNF839-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF839→partner) and Y-score (partner→ZNF839) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOXC-AS3 →	+0.751	+2.238	<.001	<.001	3	3
HNSC	MIR646 →	+0.441	+3.716	.001	.008	3	2
HNSC	IGHD3-16 →	+1.152	+3.818	.004	.009	3	2
CESC	BANF1P5 →	+0.172	+4.551	.002	.004	3	2
UCEC	RDM1 →	+0.665	+2.273	<.001	<.001	3	2
UCEC	ACD →	+0.602	+2.617	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

HOXC-AS3 by ZNF839 expression — UCEC

Explore this box plot interactively →