ZNF835

Across TCGA patient cohorts, ZNF835 mutation is significantly associated with the RNA expression of many other genes, with 5,378 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF835-associated genes across cancer lineages are EAF1, TAF13, and ALPL. Each is linked with ZNF835 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF835-to-partner and partner-to-ZNF835 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EAF1 grouped by ZNF835-low versus ZNF835-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF835→partner) and Y-score (partner→ZNF835) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EAF1 →	+0.546	+2.000	<.001	<.001	3	4
UCEC	TAF13 →	+0.690	+2.502	<.001	<.001	3	4
UCEC	ALPL →	-1.147	-1.784	<.001	<.001	3	4
LUSC	CLCN3 →	+0.429	+3.193	.006	.009	3	4
UCEC	TPD52 →	+0.421	+1.595	.008	<.001	3	4
UCEC	PRMT5 →	+0.482	+2.008	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,378 associations by consensus.

EAF1 by ZNF835 expression — UCEC

Explore this box plot interactively →