ZNF831

Across TCGA patient cohorts, ZNF831 mutation is significantly associated with the total protein of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF831-associated genes across cancer lineages are ASNS, Cyclin-B1, and GAPDH. Each is linked with ZNF831 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF831-to-partner and partner-to-ZNF831 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF831-low versus ZNF831-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF831→partner) and Y-score (partner→ZNF831) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.490	+2.115	<.001	.017	3	4
UCEC	Cyclin-B1 →	+0.617	+3.087	<.001	<.001	3	4
COAD	GAPDH →	+0.415	+1.887	.020	.029	3	4
COAD	INPP4B →	-0.365	-2.459	.005	.017	3	4
UCEC	FOXO3a_pS318_S321 →	-0.102	-1.826	.005	.001	3	3
UCEC	JNK_pT183_Y185 →	-0.175	-2.169	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

ASNS by ZNF831 expression — COAD

Explore this box plot interactively →