ZNF831

Across TCGA cell cohorts, ZNF831 mutation is significantly associated with the RNA expression of many other genes, with 1,401 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF831-associated genes across cancer lineages are ODF2L, LRRC10, and PPP4R3A. Each is linked with ZNF831 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF831-to-partner and partner-to-ZNF831 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF2L grouped by ZNF831-low versus ZNF831-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF831→partner) and Y-score (partner→ZNF831) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ODF2L →	+0.725	+2.152	.002	.005	3	3
UPPER_AERODIGESTIVE_TRACT	LRRC10 →	+0.015	+3.870	<.001	.003	3	3
CNS	PPP4R3A →	+0.559	+3.390	<.001	.003	3	3
LARGE_INTESTINE	SEPSECS →	+0.615	+2.043	<.001	.008	3	3
LARGE_INTESTINE	BEST3 →	+0.425	+2.453	.001	.006	3	3
LARGE_INTESTINE	FEM1A →	+0.525	+2.743	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,401 associations by consensus.

ODF2L by ZNF831 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →