Across TCGA patient cohorts, ZNF830 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF830-associated genes across cancer lineages are Bak, eIF4G, and FOXO3a_pS318_S321. Each is linked with ZNF830 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF830-to-partner and partner-to-ZNF830 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF830→partner) and Y-score (partner→ZNF830) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bak →	+0.328	+2.584	.005	.011	3	2
UCEC	eIF4G →	+0.318	+3.169	.027	.019	3	1
UCEC	FOXO3a_pS318_S321 →	-0.182	-2.575	.001	.010	3	1
UCEC	GAPDH →	+0.684	+3.169	.006	.018	3	1
UCEC	GSK3-a-b →	+0.145	+2.999	.021	.035	3	1
UCEC	HER3_pY1289 →	+0.113	+1.901	.004	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

ZNF830 survival (RNA) · tumor vs normal (RNA) · all ZNF830 data types