Across TCGA pan-cancer cohorts, ZNF830 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ZNF830’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where ZNF830 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF830 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
THCA, KICH, and KIRC are the cancer types where ZNF830 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF830 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.