Across TCGA patient cohorts, ZNF808 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF808-associated genes across cancer lineages are ATM, 4E-BP1, and EGFR_pY1068. Each is linked with ZNF808 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF808-to-partner and partner-to-ZNF808 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF808→partner) and Y-score (partner→ZNF808) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.417	-1.584	.001	.008	3	3
UCEC	4E-BP1 →	+0.300	+2.502	<.001	.001	3	3
UCEC	EGFR_pY1068 →	-0.224	-2.137	.002	<.001	3	2
UCEC	eIF4E →	+0.156	+1.736	.012	.006	3	2
UCEC	FoxM1 →	+0.250	+1.432	.001	.005	3	2
COAD	JNK_pT183_Y185 →	-0.234	-3.576	.038	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

ZNF808 survival (RNA) · tumor vs normal (RNA) · all ZNF808 data types