Across TCGA cell cohorts, ZNF808 mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF808-associated genes across cancer lineages are SMCP, SPRR4, and LCE2C. Each is linked with ZNF808 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF808-to-partner and partner-to-ZNF808 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF808→partner) and Y-score (partner→ZNF808) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SMCP →	+0.051	+5.169	<.001	.005	3	1
BREAST	SPRR4 →	+1.092	+5.169	<.001	.005	3	1
BREAST	LCE2C →	+0.602	+5.169	<.001	.005	3	1
BREAST	FGF16 →	+0.086	+5.781	<.001	.001	3	1
OVARY	OR10G4 →	+0.012	+4.339	.009	.001	3	1
OVARY	ZNF728 →	+0.595	+4.095	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

Exploration

ZNF808 survival (RNA) · tumor vs normal (RNA) · all ZNF808 data types