ZNF804A

Across TCGA patient cohorts, ZNF804A mutation is significantly associated with the RNA expression of many other genes, with 7,768 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF804A-associated genes across cancer lineages are ZFYVE19, OIP5, and KNSTRN. Each is linked with ZNF804A in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF804A-to-partner and partner-to-ZNF804A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZFYVE19 grouped by ZNF804A-low versus ZNF804A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF804A→partner) and Y-score (partner→ZNF804A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZFYVE19 →	+0.354	+1.638	<.001	<.001	3	7
UCEC	OIP5 →	+0.823	+2.021	<.001	<.001	3	6
UCEC	KNSTRN →	+0.519	+2.147	<.001	<.001	3	6
UCEC	SLC25A39 →	+0.264	+1.502	.002	<.001	3	6
UCEC	PSMB7 →	+0.377	+1.681	<.001	<.001	3	6
LUAD	FCER1A →	-0.881	-1.473	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,768 associations by consensus.

ZFYVE19 by ZNF804A expression — UCEC

Explore this box plot interactively →