ZNF804A

Across TCGA cell cohorts, ZNF804A mutation is significantly associated with the RNA expression of many other genes, with 388 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF804A-associated genes across cancer lineages are ELL3, TTC19, and UXS1. Each is linked with ZNF804A in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF804A-to-partner and partner-to-ZNF804A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELL3 grouped by ZNF804A-low versus ZNF804A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF804A→partner) and Y-score (partner→ZNF804A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ELL3 →	+1.060	+2.459	<.001	.008	3	3
LARGE_INTESTINE	TTC19 →	+0.538	+2.043	.002	.001	3	2
LARGE_INTESTINE	UXS1 →	-0.388	-3.105	.008	.009	3	2
LARGE_INTESTINE	MFSD6L →	+0.632	+2.115	<.001	.004	3	2
LARGE_INTESTINE	PNRC2 →	+0.504	+2.716	.001	<.001	3	2
LUNG_NSCLC_LUAD	CSKMT →	+0.525	+3.321	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 388 associations by consensus.

ELL3 by ZNF804A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →