ZNF800

Across TCGA patient cohorts, ZNF800 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF800-associated genes across cancer lineages are Cyclin-B1, p70-S6K_pT389, and Notch1. Each is linked with ZNF800 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF800-to-partner and partner-to-ZNF800 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by ZNF800-low versus ZNF800-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF800→partner) and Y-score (partner→ZNF800) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.420	+1.222	.021	.035	3	3
BLCA	p70-S6K_pT389 →	+0.256	+3.169	.006	.019	3	2
UCEC	Notch1 →	+0.134	+1.687	.003	.013	3	2
UCEC	PCNA →	+0.145	+1.222	.038	.035	3	2
UCEC	Rad50 →	-0.199	-1.459	.011	.012	3	2
UCEC	Tuberin_pT1462 →	+0.219	+1.372	.003	.022	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Cyclin-B1 by ZNF800 expression — UCEC

Explore this box plot interactively →