ZNF791

Across TCGA patient cohorts, ZNF791 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF791-associated genes across cancer lineages are PEA-15_pS116, mTOR_pS2448, and N-Cadherin. Each is linked with ZNF791 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF791-to-partner and partner-to-ZNF791 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PEA-15_pS116 grouped by ZNF791-low versus ZNF791-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF791→partner) and Y-score (partner→ZNF791) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PEA-15_pS116 →	+0.346	+1.584	.012	.036	3	3
UCEC	mTOR_pS2448 →	-0.155	-3.571	.008	.002	3	2
UCEC	N-Cadherin →	+0.199	+2.999	.016	.035	3	2
UCEC	PDCD4 →	-0.659	-3.700	<.001	.001	3	2
UCEC	ATM →	-0.510	-1.584	.004	.036	3	2
UCEC	EGFR_pY1068 →	-0.281	-2.502	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

PEA-15_pS116 by ZNF791 expression — UCEC

Explore this box plot interactively →