ZNF791

Across TCGA pan-cancer cohorts, ZNF791 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ZNF791’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ZNF791 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF791 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, LIHC, and HNSC are the cancer types where ZNF791 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF791 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.973	<.001	10	view →
LIHC	Female	II,III,IV	+0.822	<.001	9	view →
HNSC	All	All	+0.328	<.001	9	view →
LUAD	All	III,IV	−0.399	<.001	5	view →
CHOL	All	All	+1.764	<.001	3	view →
UCEC	All	All	−0.363	.009	2	view →
KICH	All	All	−0.434	.011	1	view →
KIRC	All	All	+0.151	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

ZNF791–THCA

Open the THCA breakdown →