ZNF791

Across TCGA cell cohorts, ZNF791 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF791-associated genes across cancer lineages are XAGE5, ODF4, and MUC5B. Each is linked with ZNF791 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF791-to-partner and partner-to-ZNF791 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE5 grouped by ZNF791-low versus ZNF791-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF791→partner) and Y-score (partner→ZNF791) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
OVARY	ODF4 →	+0.035	+5.196	<.001	.005	3	1
LARGE_INTESTINE	MUC5B →	+2.287	+3.064	<.001	.009	3	1
LARGE_INTESTINE	GALR3 →	+0.084	+3.602	.004	.005	3	1
LARGE_INTESTINE	SLCO1C1 →	+0.293	+2.842	.006	.003	3	1
LARGE_INTESTINE	GP2 →	+0.456	+2.819	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

XAGE5 by ZNF791 expression — OVARY

Explore this box plot interactively →