ZNF790-AS1

Across TCGA pan-cancer cohorts, ZNF790-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF790-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher ZNF790-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF790-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

LGG, ACC, and UCS are the cancer types where ZNF790-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.645	0.822	<.001	46	view →
ACC	DFS	Median	All	0.266	0.652	<.001	42	view →
UCS	DFS	Tertile	III,IV	0.580	0.176	<.001	40	view →
PAAD	DFS	Median	All	0.517	0.218	<.001	39	view →
HNSC	DFS	Median	IV	0.614	0.478	.009	35	view →
PRAD	DFS	Tertile	All	0.883	0.972	<.001	22	view →
BRCA	OS	Tertile	II,III,IV	0.980	0.940	.006	21	view →
KIRP	DFS	Median	All	0.948	0.589	.001	18	view →
UCEC	DFS	Quartile	All	0.633	0.780	.008	18	view →
KIRC	DFS	Median	All	0.859	0.728	.011	14	view →
LUAD	DFS	Tertile	All	0.830	0.741	.011	12	view →
GBM	OS	Quartile	All	0.568	0.277	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF790-AS1–LGG (DFS)

Open the LGG breakdown →