ZNF790-AS1

Across TCGA pan-cancer cohorts, ZNF790-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ZNF790-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ZNF790-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF790-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and HNSC are the cancer types where ZNF790-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF790-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.279	<.001	10	view →
KIRC	Male	All	−0.661	<.001	10	view →
HNSC	Female	II,III,IV	−0.648	<.001	10	view →
COAD	Male	All	−0.578	<.001	9	view →
THCA	Male	All	−0.477	<.001	7	view →
UCEC	All	III,IV	−1.608	<.001	6	view →
STAD	All	All	−0.615	<.001	6	view →
LIHC	All	All	+0.337	<.001	5	view →
CHOL	All	All	+1.900	<.001	4	view →
READ	All	II,III,IV	−0.800	.021	4	view →
ESCA	All	All	−0.570	.023	2	view →
LUAD	Male	All	+0.547	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ZNF790-AS1–KICH

Open the KICH breakdown →