Across TCGA cell cohorts, ZNF79 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible ZNF79-associated genes across cancer lineages are TTLL8, MBD3L3, and MBD3L4. Each is linked with ZNF79 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF79-to-partner and partner-to-ZNF79 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF79→partner) and Y-score (partner→ZNF79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TTLL8 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	MBD3L3 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	MBD3L4 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	OR1C1 →	+0.016	+4.906	<.001	.006	3	1
LARGE_INTESTINE	ELOA3P →	+0.100	+3.819	.001	.003	3	1
LARGE_INTESTINE	SPEM3 →	+0.013	+3.347	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ZNF79 survival (RNA) · tumor vs normal (RNA) · all ZNF79 data types