Across TCGA cell cohorts, ZNF785 mutation is significantly associated with the RNA expression of many other genes, with 104 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF785-associated genes across cancer lineages are PDE6H, FMO1, and GABRG1. Each is linked with ZNF785 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF785-to-partner and partner-to-ZNF785 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF785→partner) and Y-score (partner→ZNF785) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	PDE6H →	+0.053	+3.772	.001	.007	3	2
LARGE_INTESTINE	FMO1 →	+0.115	+3.658	<.001	.005	3	1
LARGE_INTESTINE	GABRG1 →	+0.009	+3.196	.001	.007	3	1
BLOOD_Leukemia	SLC32A1 →	+0.698	+2.901	<.001	.002	3	1
BLOOD_Leukemia	VIPR2 →	+2.071	+3.507	<.001	.003	3	1
BLOOD_Leukemia	LGI1 →	+0.043	+3.539	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

Exploration

ZNF785 survival (RNA) · tumor vs normal (RNA) · all ZNF785 data types