ZNF784

Across TCGA patient cohorts, ZNF784 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF784-associated genes across cancer lineages are RNU7-125P, CTBP2P1, and C3orf84. Each is linked with ZNF784 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF784-to-partner and partner-to-ZNF784 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-125P grouped by ZNF784-low versus ZNF784-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF784→partner) and Y-score (partner→ZNF784) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-125P →	+0.701	+3.105	<.001	.001	3	2
CESC	CTBP2P1 →	+0.221	+5.397	<.001	<.001	3	1
CESC	C3orf84 →	+0.661	+4.200	<.001	.004	3	1
CESC	RNU6-1308P →	+0.211	+4.559	.007	.006	3	1
CESC	IGKV2-10 →	+0.281	+4.060	<.001	.004	3	1
CESC	MIR5189 →	+0.251	+4.984	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

RNU7-125P by ZNF784 expression — UCEC

Explore this box plot interactively →