ZNF784

Across TCGA pan-cancer cohorts, ZNF784 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ZNF784’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where ZNF784 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF784 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LIHC, STAD, and LUAD are the cancer types where ZNF784 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF784 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+1.025	<.001	8	view →
STAD	All	II,III,IV	+0.377	.015	3	view →
LUAD	All	All	−0.342	<.001	3	view →
KICH	All	All	−0.340	.024	3	view →
CHOL	All	All	+0.770	<.001	2	view →
COAD	Male	IV	−0.490	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

ZNF784–LIHC

Open the LIHC breakdown →