ZNF784

Across TCGA cell cohorts, ZNF784 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,655 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF784-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Regulation of chromatin organization. Each is linked with ZNF784 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF784-to-partner and partner-to-ZNF784 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by ZNF784-low versus ZNF784-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF784→partner) and Y-score (partner→ZNF784) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.096	+0.973	<.001	.001	3	17
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.154	+0.752	<.001	<.001	3	17
BONE	Regulation of chromatin organization →	+0.100	+0.903	.001	.001	3	15
BREAST	Regulation of protein localization to endoplasmic reticulum →	+0.121	+0.955	<.001	<.001	3	14
KIDNEY	Regulation of nucleocytoplasmic transport →	+0.074	+0.650	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.196	+1.103	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,655 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by ZNF784 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →