ZNF784

Across TCGA cell cohorts, ZNF784 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF784-associated genes across cancer lineages are MBD3L2B, FCGR3B, and NUPR2. Each is linked with ZNF784 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF784-to-partner and partner-to-ZNF784 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MBD3L2B grouped by ZNF784-low versus ZNF784-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF784→partner) and Y-score (partner→ZNF784) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MBD3L2B →	+0.036	+5.969	<.001	.001	3	1
LARGE_INTESTINE	FCGR3B →	+0.174	+4.467	<.001	.004	3	1
LARGE_INTESTINE	NUPR2 →	+0.395	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MBD3L2B by ZNF784 expression — BLOOD_Leukemia

Explore this box plot interactively →