ZNF780B

Across TCGA cell cohorts, ZNF780B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,379 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF780B-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Heterochromatin formation, and Nuclear-transcribed mRNA catabolic process. Each is linked with ZNF780B in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF780B-to-partner and partner-to-ZNF780B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by ZNF780B-low versus ZNF780B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF780B→partner) and Y-score (partner→ZNF780B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.138	+0.703	<.001	.001	3	14
BONE	Heterochromatin formation →	+0.066	+0.659	<.001	.002	3	14
STOMACH	Nuclear-transcribed mRNA catabolic process →	+0.056	+1.127	.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.055	+0.950	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.083	+0.708	<.001	<.001	3	13
BONE	Epigenetic regulation of gene expression →	+0.072	+0.938	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,379 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by ZNF780B expression — LUNG_SCLC

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