ZNF780B

Across TCGA cell cohorts, ZNF780B mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF780B-associated genes across cancer lineages are CCDC185, C9orf92, and MAGEA9. Each is linked with ZNF780B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF780B-to-partner and partner-to-ZNF780B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC185 grouped by ZNF780B-low versus ZNF780B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF780B→partner) and Y-score (partner→ZNF780B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCDC185 →	+0.048	+4.635	<.001	.003	3	1
SOFT_TISSUE	C9orf92 →	+0.144	+4.369	<.001	.008	3	1
BLOOD_Lymphoma	MAGEA9 →	+1.510	+3.192	.008	.008	3	1
BLOOD_Lymphoma	LRMDA →	+0.958	+3.675	<.001	.005	3	1
BLOOD_Lymphoma	IRX6 →	+0.168	+3.373	<.001	.005	3	1
BLOOD_Lymphoma	SLAMF9 →	+0.133	+3.906	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

CCDC185 by ZNF780B expression — SOFT_TISSUE

Explore this box plot interactively →